Strigolactones (SLs) and karrikins (KARs) are both butenolide molecules that play essential roles in plant growth and development. SLs are phytohormones, with SLs having known functions within the plant they are produced in, while KARs are found in smoke emitted from burning plant matter and affect seeds and seedlings in areas of …
γ-Butyrolactone, a five-membered lactone moiety, is one of the most privileged structures of diverse natural products and biologically active small molecules having a broad spectrum of biological and pharmacological activities [1].Several γ-butyrolactone-containing drugs have been FDA-approved and used in clinics for …
The production of gamma-butyrolactone and/or butane-1,4-diol by catalytic hydrogenation of dialkyl esters of C 4 dicarboxylic acids, such as maleic acid, fumaric acid, succinic acid, and acetylenedicarboxylic acid, has been described on various occasions. In some cases the hydrogenation reaction results in production of tetrahydrofuran as a co ...
γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of diverse natural products and biologically active small molecules.Because of their broad spectrum of biological and pharmacological activities, synthetic methods for γ-butyrolactones have received significant attention from synthetic and medicinal chemists …
Our results provide insights into plant metabolite production in wood tissues and, overall, demonstrate that combining high spatial resolution TOF-SIMS imaging and MS/MS structural ...
γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of diverse natural products and biologically …
3-hydroxy-γ-butyrolactone (3HBL) is a building block for many valuable drugs and is synthesized via a costly industrial process. Martin et al. engineer a novel biosynthetic pathway for the ...
Mol Plant Microbe Interact. 2004 Sep;17(9):951-7. doi: 10.1094/MPMI.2004.17.9.951. ... In this work, the attKLM operon of A. tumefaciens C58 was shown to be involved in an assimilative pathway of gamma-butyrolactone (GBL), gamma-hydroxybutyrate (GHB), and succinate semialdehyde (SSA), in which AttM and AttL are key enzymes for GBL and …
Antineoplastic Agents. 4-Butyrolactone. In the process development of lovastatin using Aspergillus terreus DRCC 152 in solid state fermentation, we have isolated a new butyrolactone-IV (3) along with the previously reported butyrolactone-I (1) and butyrolactone-II (2) produced under submerged conditions. The structure of compound …
A new butyrolactone derivative, namely butyrolactone VIII (1), and six known butyrolactones (2–7) were separated from the ethyl acetate (EtOAc) extract of the fermentation broth of a fungus, Aspergillus terreus MXH-23. The chemical structures of these metabolites were identified by analyzing their nuclear magnetic resonance (NMR) …
An α-methylene-γ-butyrolactone derivative, (3S,4R)-3-carboxy-2-methylene-heptan-4-olide (1), having a toxic effect on inducing fruit rot was isolated from Lasiodiplodia theobromae. ... The dynamism of these pathogens is evident based on their ubiquitous presence in a broad range of niches and host plants, suggesting their functional role to ...
Six new butyrolactone derivatives (1, 2a/2b, 3a/3b and 4), together with another two known derivatives (5 and 6) were isolated from the endophytic fungus …
Native American food and medicinal plants. 3. alpha-Methylene butyrolactone from Erythronium grandiflorum Pursh. Native American food and medicinal plants. 3. alpha-Methylene butyrolactone from Erythronium grandiflorum Pursh J Ethnopharmacol. 1985 Sep;14(1):99-101. doi: 10.1016/0378-8741(85)90034-0. ...
1. Introduction. γ-Butyrolactone, a five-membered heterocycle containing ester functionality, has been broadly studied in the drug discovery field since it is one of the privileged structures of biologically active small molecules.Several γ-butyrolactone-containing drugs have been FDA-approved and used in clinic for diverse purposes such …
greening disease. Gamma-butyrolactone (GBL), a primary component of the D. citri pheromone, failed to lure adult psyllids to sticky traps deployed in infested citrus groves in numbers greater than those captured by non-baited traps. The ineffectiveness of the single component as a trap-lure suggests that other important signals may be lacking.
Six new butyrolactone derivatives (1, 2a/2b, 3a/3b and 4), together with another two known derivatives (5 and 6) were isolated from the endophytic fungus Talaromyces sp. CPCC 400783. Their ...
Gamma-Butyrolactone (GBL) is the simplest 4-carbon lactone, a colorless liquid, miscible in water, and has a weak odor. ... GBL is used as a parent chemical to produce herbicides and as a plant ...
The search for toxins produced by L. theobromae may allow for a better understanding of disease pathogenesis and facilitate screening programs for disease-resistant plants. In this paper, we report the isolation and structural elucidation of a novel toxin, (3 S,4 R )-3-carboxy-2-methylene-heptan-4-olide ( 1 ), together with decumbic …
All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. Please see the following for information about the library and its accompanying search program.
Plant biostimulants prove beneficial to plants by improving their growth. Microbial inoculants, single or consortia, naturally improve plant growth and performance without using any agrochemicals in the field. They can act as biofertilizers, soil improvers, growth regulators, stress relievers, and biocontrol agents.
The 2021 Regulations placed two controlled drugs, Gamma-Butyrolactone (GBL) and 1,4-Butanediol (1,4-BD), which have legitimate uses in industry, under stricter control, meaning that industrial ...
When gamma-butyrolactone was given intracardially at 136 mg/kg bw, the plasma levels was 500 ug/mL immediately upon dosing, about 400 ug/mL after 30 minutes and slightly more than 100 ug/mL after 2 hours but then …
Gram-negative bacteria most often use N-acyl homoserine lactones (AHLs) as intercellular quorum-sensing signal molecules. In this study, it was demonstrated that rice plants contain AHL mimic molecules that are very sensitive to the highly specific AiiA lactonase enzyme and can activate three different AHL bacterial biosensors, indicating that the …
The Middle East and Africa gamma butyrolactone market expands at a CAGR of 2.7% in the forecast period and is estimated to reach USD 63,121.40 thousand by 2030. ... Along with it, gamma butyrolactone serves as a plant growth regulator and stabilizer for pesticides containing phosphorus and chlorohydrocarbons. Thus the high population ...
In agriculture, GBL has been explored as a precursor for producing plant protection agents, helping improve crop yields and resistance against pests. In summary, gamma …
IUPAC Standard InChIKey: YEJRWHAVMIAJKC-UHFFFAOYSA-N Copy CAS Registry Number: 96-48-0 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Species with the same structure:
Nitta K, Fujita N, Yoshimura T, Arai K, Yamamoto Y. (1983) Metabolic products of Aspergillus terreus. IX. Biosynthesis of butyrolactone derivatives was …
PubMed:Gamma-butyrolactone's discriminability and effect on low rates of lever pressing by rats: alone and in combination with D-amphetamine and naloxone. PubMed:Native American food and medicinal plants. 3. alpha-Methylene butyrolactone from Erythronium grandiflorum Pursh.
It has been estimated that almost 10% of natural products contain in their structure a γ-butyrolactone ring 1. This type of molecules is produced by algae, ...
Molecular analysis by parallel tandem mass spectrometry (MS/MS) imaging contributes to the in situ characterization of biosynthetic intermediates which is …
These ralfuranones were also detected in vascular exudates from host plants infected with OE1-1. Deletion of ralA, which encodes an enzyme for ralfuranone biosynthesis, reduced the virulence of OE1-1 in tomato plants. Virulence was restored by complementation of the ralA gene. The results suggest that ralfuranones play important …
A-factor homologues having a γ-butyrolactone structure have been found in various Streptomyces species, such as S. bikiniensis, S. coelicolor A3(2), S. cyaneofuscatus, S. lavendulae, S. iae, and S. viridochromogenes (reviewed in the works of Horinouchi 17,18 and Yamada and Nihira 19).Examples include iae butanolides (VBs), …
Endophytes coexist with plants, in part, due to cellulase that allow saccharification of plant cell walls. The cellulase enzymes found in naturally occurring endophytes may exhibit stronger activity and more specificity than commercially available cellulase for enzyme-assisted extraction of compounds from medicinal plant materials.
The chemical constituents and biological activities of the terrestrial Aspergillus flavipes MM2 isolated from Egyptian rice hulls are reported. Seven bioactive compounds were obtained, of which one sterol: ergosterol (1), four butyrolactones: butyrolactone I (2), aspulvinone H (3), butyrolactone-V (6) and 4,4'-diydroxypulvinone (7), along with 6 …
Journal of Ethnopharmacology, 14 (1985t 9901 99 Eisevier Scientific Publishers Ireland Ltd. Short communication NATIVE AMERICAN FOOD AND MEDICINAL PLANTS. 3. a-METHYLENE BUTYROLACTONE FROM ERYTHRONIUM GRANDIFLORUM PURSH* KENNETH B. DIAMOND, GUYLYN R. WARREN and …
GHB takes effect in 15 to 30 minutes, and the effects last 3 to 6 hours. Low doses of GHB produce nausea. At high doses, GHB overdose can result in: • Unconsciousness, seizures, slowed heart rate, greatly slowed breathing, lower body temperature, vomiting, nausea, coma, and death. Regular use of GHB can lead to addiction and withdrawal that ...
